Behavioral Changes as the Earliest Clinical Manifestation of Progressive Supranuclear Palsy
نویسندگان
چکیده
BACKGROUND The clinical and pathological heterogeneity of progressive supranuclear palsy (PSP) is well established. Even with a well-defined clinical phenotype and a thorough laboratory workup, PSP can be misdiagnosed, especially in its early stages. CASE REPORT A 52-year-old woman, who we initially diagnosed with a behavioral variant of frontotemporal dementia developed parkinsonian features, which then progressed to gait instability and gaze abnormality. CONCLUSIONS We report herein a pathologically confirmed case of PSP presenting with behavioral changes including agitation and irritability, which eventually led to the cardinal symptoms of progressive supranuclear palsy.
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2010